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Time-kill curve of AM-228 and gatifloxacin on M. chelonae. A 3-log reduction was seen at 48 h after treatment with AM-228 at 2× MIC or 4× MIC. Gatifloxacin treatment at 2× MIC and 4× MIC provided a 3-log reduction at 48 h posttreatment. However, there was bacterial regrowth seen with 1× MIC and 2× MIC at 120 h after treatment.
