FIG 7.

Effect of penisin on MRSA and comparison with known antimicrobial agents. (A) Penisin-mediated killing kinetics of MRSA (n = 3). Symbols represent the viable cell counts of MRSA at different time intervals along with 1× (4 μM), 2× (8 μM), and 5× (20 μM) MIC of penisin. Error bars represent SD. All groups were compared with the untreated control for statistical significance. *, P < 0.05 in comparison to control. (B) TEM images of MRSA after treatment with penisin. (C) The viable cell percentage for penisin and other known antimicrobial agents. Error bars show SD (n = 3). *, P < 0.05 in comparison to the untreated control. NS, nisin; AMP, ampicillin; Chm, chloramphenicol; Stp, streptomycin. All bacterial samples and purified peptide were prepared in PBS.