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Acidification and extracellular DNA increases P. aeruginosa resistance to aminoglycosides
| Growth condition | MIC (μg/ml)a |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gm | Tm | Km | Ak | Sm | Nm | Cm | Tet | Cb | |
| LB (pH 7) | 4 | 1 | 4 | 4 | 50 | 60 | 80 | 20 | 40 |
| LB (pH 5.5) | 32 | 8 | 16 | 16 | 100 | >128 | 80 | 20 | 80 |
| LB + 0.2% DNA | 32 | 8 | 16 | 32 | >200 | >128 | 80 | 20 | 160 |
Gm, gentamicin; Tm, tobramycin; Km, kanamycin; Ak, amikacin; Sm, streptomycin; Nm, neomycin; Cm, chloramphenicol; Tet, tetracycline; Cb, carbenicillin.
