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editorial

. 2016 Jan 6;14:4. doi: 10.1186/s12967-015-0760-1

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© Broomé and Donker. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effects of simulated increase of VA-ECMO from 0 to 2.1 L/min left (black) and right (gray) ventricular pressure–volume loops. All other model parameters such as cardiac contractility, intravascular blood volume, systemic and pulmonary vascular resistance are unchanged. The results indicate an increase in left ventricular loading, that is represented by movement of loops upward (higher pressures) and rightward (higher volumes)