Table 1.

Patients characteristics and univariate analyses of overall survival

Characteristic	Number	%	Overall survival
			HR	95%CI	P-value*
Gender
Male (ref)	232	78.4	1
Female	64	21.6	0.678	0.506–0.908	0.009
Age (years)	55 (27–78)
Length (cm)
≤6 (ref)	107	35.8	1
>6	189	64.2	1.406	1.097–1.803	0.007
Location					0.862
Upper	61	20.6	1
Middle	209	70.6	1.118	0.821–1.524	0.479
Lower	26	8.8	1.082	0.844–1.388	0.533
Anastomosis
Neck	102	26.3
Thorax	194	73.7	1.014	0.892–1.153	0.833
Histological grade					0.323
Well	39	13.2	1
Moderate	191	64.5	0.085	0.664–1.353	0.085
Poor	66	22.3	1.104	0.891–1.368	0.836
yT stage					<0.0001
T0 (ref)	100	33.9	1
T1	10	3.4	1.381	0.715–2.666	0.334
T2	58	20.0	0.968	0.816–1.149	0.713
T3	80	27.0	1.218	1.094–1.356	0.000
T4a	15	5.1	1.284	1.146–1.439	0.000
T4b	33	11.1	1.183	1.102–1.269	0.000
yN stage					<0.0001
N0 (ref)	207	70.0	1
LN1-2	56	18.9	1.559	1.149–2.114	0.004
LN3-6	21	7.1	1.580	1.245–2.007	0.000
LN ≥7	12	4.0	1.498	1.227–1.829	0.000
Resection					<0.0001
R0 (ref)	240	81.1	1
R2	56	18.9	1.405	1.210–1.632
ypStage 7th UICC
0 (T0N0M0 ref)	78	26.3	1		<0.0001
ypStage I	46	15.5	0.994	0.641–1.391	0.771
ypStage IIA	52	17.6	1.367	1.126–1.660	0.001
ypStage IIB	25	8.4	1.080	0.960–1.215	0.198
ypStage IIIA	38	12.8	1.223	1.122–1.333	0.000
ypStage IIIB	7	2.4	1.211	1.045–1.403	0.007
ypStage IIIC	50	16.9	1.198	1.131–1.269	0.000

^*P-values calculated using Kaplan-Meier methods. 95% CI, 95% confidence interval; HR, hazard ratio; UICC, Union for International Cancer Control.