Table 1.
Tag single nucleotide polymorphisms (SNPs) selected from the HapMap database
| Repair pathway and genes | Gene location | SNP (rs no.) | Location | Base change | Rare allele frequency in HapMap HCB |
|---|---|---|---|---|---|
| Base excision repair | |||||
| XRCC1 | 19q13.2 | rs25487 | Exon6 | A/G | 0.274 |
| rs1799782 | Exon10 | C/T | 0.244 | ||
| rs3213334 | Intron3 | C/T | 0.102 | ||
| rs3213255 | Intron2 | C/T | 0.144 | ||
| Nucleotide excision repair | |||||
| XPA | 9q22.3 | rs3176720 | Intron5 | A/C | 0.100 |
| XPC | 3p25 | rs2808668 | Intron2 | C/T | 0.487 |
| rs2229090 | 3'UTR | C/G | 0.282 | ||
| rs2228001 | Exon16 | A/C | 0.378 | ||
| rs2733533 | Intron15 | A/C | 0.089 | ||
| XPD | 19q13.3 | rs3729584 | Intron10 | A/G | 0.227 |
| rs1799787 | Intron19 | C/T | 0.068 | ||
| rs238415 | Intron17 | C/G | 0.475 | ||
| rs238406 | Exon6 | G/T | 0.407 |
HCB, Hapmap-Han Chinese in Beijing.