Table 5.
Correlations between the accuracy of sentinel lymph node biopsy (identification and false-negative rates) and clinicopathological factors in breast cancer patients after neodjuvant chemotherapy
| Clinicopathological factors | Identification rate (43/51) | False-negative rate (6/31) | ||
|---|---|---|---|---|
| n (%) | P | n (%) | P | |
| Age | ||||
| ≥50 | 22/27 (81.5%) | 0.838 | 4/20 (20%) | 1.000 |
| <50 | 21/24 (87.5%) | 2/11 (18.2%) | ||
| Method of lymphatic mapping | ||||
| Blue dye only | 5/8 (62.5%) | 0.073 | 0/2 | 0.753 |
| Radioactive colloid only | 5/7 (71.4%) | 1/4 (25%) | ||
| Both | 33/36 (82.1%) | 5/25 (20%) | ||
| Location of radiocolloid injection | ||||
| Subareolar | 12/17 (70.6%) | 0.134 | 2/8 (25%) | 0.634 |
| Peritumoral | 31/34 (91.7%) | 4/23 (17.4%) | ||
| Operator | ||||
| Chief physician | 26/29 (89.7%) | 0.432 | 4/19 (21.1%) | 0.836 |
| Associate Chief Physician | 12/16 (75.0%) | 1/8 (12.5%) | ||
| Other | 5/6 (83.3%) | 1/4 (25%) | ||
| Tumor localization | ||||
| Upper outer | 16/19 (84.2%) | 0.992 | 3/13 (23.1%) | 0.905 |
| Central | 10/12 (83.3%) | 1/6 (16.7%) | ||
| Other | 17/20 (85.0%) | 2/12 (16.7%) | ||
| Histological type | ||||
| Invasive ductal carcinoma | 32/39 (82.1%) | 0.653 | 5/23 (21.7%) | 0.744 |
| Invasive lobular carcinoma | 8/9 (88.9%) | 1/6 (16.7%) | ||
| Composite carcinoma | 3/3 (100%) | 0/2 | ||
| Tumor classification | ||||
| T1-2 | 29/32 (90.1%) | 0.226 | 2/20 (10%) | 0.151 |
| T3-4 | 14/19 (73.7%) | 4/11 (41.7%) | ||
| Clinical nodal status before treatment | ||||
| N1 | 26/28 (92.9%) | 0.143 | 1/18 (5.9%) | 0.059 |
| N2-3 | 17/23 (73.9%) | 5/13 (35.8%) | ||
| Pathologic tumor response | ||||
| Grade 1–2 | 12/16 (75%) | 0.450 | 4/11 (36.4%) | 0.175 |
| Grade 3–4 | 21/24 (87.5%) | 2/16 (12.5%) | ||
| Grade 5 | 10/11 (90.9%) | 0/4 | ||
| Pathologic response in lymph node | ||||
| N-B | 5/7 (71.4%) | 0.470 | 2/5 (40%) | 0.241 |
| N-C | 26/31 (83.9%) | 4/26 (15.4%) | ||
| N-D | 12/13 (92.3%) | — | ||