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. 2014 Oct 23;5(6):550–555. doi: 10.1111/1759-7714.12131

Table 5.

Correlations between the accuracy of sentinel lymph node biopsy (identification and false-negative rates) and clinicopathological factors in breast cancer patients after neodjuvant chemotherapy

Clinicopathological factors Identification rate (43/51) False-negative rate (6/31)
n (%) P n (%) P
Age
 ≥50 22/27 (81.5%) 0.838 4/20 (20%) 1.000
 <50 21/24 (87.5%) 2/11 (18.2%)
Method of lymphatic mapping
 Blue dye only 5/8 (62.5%) 0.073 0/2 0.753
 Radioactive colloid only 5/7 (71.4%) 1/4 (25%)
Both 33/36 (82.1%) 5/25 (20%)
Location of radiocolloid injection
 Subareolar 12/17 (70.6%) 0.134 2/8 (25%) 0.634
 Peritumoral 31/34 (91.7%) 4/23 (17.4%)
Operator
 Chief physician 26/29 (89.7%) 0.432 4/19 (21.1%) 0.836
 Associate Chief Physician 12/16 (75.0%) 1/8 (12.5%)
 Other 5/6 (83.3%) 1/4 (25%)
Tumor localization
 Upper outer 16/19 (84.2%) 0.992 3/13 (23.1%) 0.905
 Central 10/12 (83.3%) 1/6 (16.7%)
 Other 17/20 (85.0%) 2/12 (16.7%)
Histological type
 Invasive ductal carcinoma 32/39 (82.1%) 0.653 5/23 (21.7%) 0.744
 Invasive lobular carcinoma 8/9 (88.9%) 1/6 (16.7%)
 Composite carcinoma 3/3 (100%) 0/2
Tumor classification
 T1-2 29/32 (90.1%) 0.226 2/20 (10%) 0.151
 T3-4 14/19 (73.7%) 4/11 (41.7%)
Clinical nodal status before treatment
 N1 26/28 (92.9%) 0.143 1/18 (5.9%) 0.059
 N2-3 17/23 (73.9%) 5/13 (35.8%)
Pathologic tumor response
 Grade 1–2 12/16 (75%) 0.450 4/11 (36.4%) 0.175
 Grade 3–4 21/24 (87.5%) 2/16 (12.5%)
 Grade 5 10/11 (90.9%) 0/4
Pathologic response in lymph node
 N-B 5/7 (71.4%) 0.470 2/5 (40%) 0.241
 N-C 26/31 (83.9%) 4/26 (15.4%)
 N-D 12/13 (92.3%)