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Relative frequency (RF) of major subtypes of female lung cancer cases by year of diagnosis. Trend tests were analyzed for squamous cell carcinoma, SCC (Z = −8.750, P < 0.0001); adenocarcinoma, ADC (Z = 16.998, P < 0.0001); small cell carcinoma, SCLC (Z = −0.933, P = 0.3508); large cell carcinoma, LCC (Z = 3.079, P = 0.0021); and adeno-squamous carcinoma ASC (Z = −6.918, P < 0.0001).
