Table 1.
Validation (qPCR) of genes involved in bile acid metabolism after S. Typhimurium infection.
| Gene | Day 2 | Day 6 | ||
|---|---|---|---|---|
| qPCR | Array | qPCR | Array | |
| APOA1 | −50.00** | −33.32** | −1.76 | – |
| C-FOS | 7.00* | – | 1.87 | – |
| C-JUN | 1.87 | – | 1.33 | – |
| FABP2 | −50.00* | −48.16*** | −2.58 | – |
| FABP6 | −200.00** | −56.24* | −2.28 | – |
| IL-1B | 30.22** | 3.4* | 2.92 | – |
| IL-6 | 1.69 | – | −1.91 | – |
| NR1H4 (FXR) | −3.73 | −4.68* | 1.34 | 2.02* |
| PPARG | 1.70 | 1.88** | 1.39 | – |
| RXRG | −4.09* | −2.92** | 1.56 | – |
| SLC10A2 (ASBT) | −1.92* | – | 1.38 | |
| STAT3 | 1.64 | 1.57 | −1.6* | |
| TLR2 | 2.99* | 1.57* | 3.43 | 2.41* |
| TLR4 | 10.44* | 1.88* | 2.25 | 3.52* |
| TLR9 | −1.79 | −1.29 | −1.92* | |
| TNF-α | 8.68* | 1.59* | −1.26 | – |
All values are expressed in fold change (FC) compared to controls. Asterisks indicate statistically significant values (compared to controls).
* P < 0.05; ** P < 0.01; *** P < 0.001.