Table 1. Comparison of the differences in stability of WT and Mut RNA duplexes with particular oligonucleotides, for all the analyzed SNP types.

The greater the difference, the more selective hybridization was observed.

SNP	WT-Mut ΔΔG°37 (kcal/mol)
	7-nt inhibitor	10-nt inhibitor	13-nt gapmer
C/G	4.69	3.96	-8.11
A/G	1.72	1.44	-5.31
G/A (APP717)	1.6	4.65	-0.5
G/A (SNCA46)	4.07	7.53	-3.36
G/A (SNCA53)	4.11	5.54	-2.7
C/U	2.29	0.48	-2.62
G/C	7.94	9.56	-9.76