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. 2015 Nov 10;170(1):136–146. doi: 10.1104/pp.15.01444

Table II. Summary of candidate genes of metabolic QTLs repeatedly identified or cross-validated using different populations and approaches.

Metabolic Trait Candidate Gene Gene Interval Annotation Cross-Validation
bp
l-Pipecolate GRMZM2G139852 chr1:24225117-24229054 Unknown ZYE1, ZYE2, GWAS
l-Met GRMZM2G450498 chr1:223161919-223165331 Met γ-lyase BBE1, BBE2, ZYE1
4-Coumaric acid r1 chr10:138462252-138471072 Basic helix-loop-helix DNA-binding BBE1, ZYE1, ZYE2
Dicoumaroylputrescine GRMZM2G311059 chr10:139838952-139839963 R2R3-MYB domain protein BBE1, BBE2, ZYE2
LPC(1-acyl 16:1)-2 GRMZM2G121783 chr8:171204852-171206144 RNase III ZYE1, GWAS
Phenolamides GRMZM2G011655 chr6:55648330-55654264 Terpenoid synthase ZYE2, GWAS
LPC(1-acyl 18:1) GRMZM5G864771 chr6:166954568-166958991 Triglyceride lipase BBE1, ZYE2
GRMZM2G156620 chr6:165800173-165802545 β-Ketoacyl-acyl-carrier protein synthaseI BBE1, ZYE2
Triornicin GRMZM2G154687 chr6:165626650-165628898 Triacylglycerol lipase, class 3 BBE1, ZYE2, GWAS
Tryptamine GRMZM2G021277 chr10:82848693-82850823 Aromatic-l-amino acid decarboxylase BBE2, GWAS
GRMZM2G021388 chr10:82837506-82839784 Aromatic-l-amino acid decarboxylase BBE2, GWAS
l-Carnitine GRMZM5G808017 chr2:193648937-193649473 Palmitoyl-CoA hydrolase, acyl-CoA hydrolysis BBE1, BBE2, ZYE1, ZYE2
GRMZM5G860226 chr2:193644136-193645990 Palmitoyl-CoA hydrolase, acyl-CoA hydrolysis BBE1, BBE2, ZYE1, ZYE2
GRMZM2G395244 chr2:217644444-217647139 EF-Hand1, calcium-binding site ZYE1, ZYE2, GWAS
N-Acetyldopamine bx1 chr4:3256234-3258478 Indole-3-glycerol phosphate lyase ZYE1, ZYE2
DIMBOA bx1 chr4:3256234-3258478 Indole-3-glycerol phosphate lyase ZYE1, ZYE2
Acetylintermedine GRMZM2G032962 chr1:277141292-277151152 Chaperone DnaJ domain superfamily protein BBE1, BBE2, ZYE2
GRMZM2G031138 chr1:278022167-278026951 UDP-glucuronosyl/UDP-glucosyltransferase BBE1, BBE2, ZYE2
GRMZM2G174570 chr8:21445191-21449321 Glutathione metabolism-like domain ZYE1, ZYE2, GWAS
GRMZM2G371276 chr8:21295629-21296981 Calmodulin-dependent protein kinases ZYE1, ZYE2, GWAS
Trp metabolite GRMZM2G021277 chr10:82848693-82850823 Aromatic-l-amino acid decarboxylase BBE2, GWAS
GRMZM2G021388 chr10:82837506-82839784 Aromatic-l-amino acid decarboxylase BBE2, GWAS
Caffeic acid derivative GRMZM2G177412 chr10:144614306-144619343 Shikimate dehydrogenase BBE1, ZYE1
Thiamin GRMZM2G112956 chr4:156756845-156760798 NADH dehydrogenase (ubiquinone) BBE1, ZYE1
N-Coumaroyl-spermidine derivative GRMZM2G066049 chr10:1087065-1088682 Agmatine coumaroyltransferase BBE2, GWAS
GRMZM2G066142 chr10:1084103-1085734 Agmatine coumaroyltransferase BBE2, GWAS
Vitexin GRMZM2G043295 chr9:130524722-130526606 Flavanol-3-O-glucosyltransferase ZYE1, GWAS
Apigenin C-pentosyl-C-pentoside GRMZM2G059590 chr8:153858072-153864534 Unknown BBE1, GWAS
Tricin derivative GRMZM2G097841 chr10:143746242-143748475 Anthocyanidin reductase BBE1, BBE2, GWAS
GRMZM2G097854 chr10:143738314-143740641 Leucoanthocyanidin reductase BBE1, BBE2, GWAS
GRMZM2G431504 chr10:143752078-143754011 Leucoanthocyanidin reductase BBE1, BBE2, GWAS
Chrysoeriol O-rhamnosyl-O-hexoside p1 chr1:48117497-48128047 A-type R2R3-MYB protein BBE1, BBE2, GWAS
N-Feruloylagmatine GRMZM5G836567 chr10:137286273-137294014 Spc97/Spc98 family of spindle pole body component BBE1, ZYE2, GWAS
Methoxylated flavonoid 3-O-hexoside GRMZM2G104710 chr10:1919386-1920869 O-Methyltransferase family protein BBE1, BBE2, GWAS
Methoxylated flavonoid di-O-hexoside GRMZM2G104710 chr10:1919386-1920869 O-Methyltransferase family protein BBE1, BBE2, GWAS