Table 2. Nucleic acid release by R. erythropolis IBBPo1 cells after 1% organic solvents exposure.
Cell permeabilitya | Organic solvents (log P OW b) | ||||||
---|---|---|---|---|---|---|---|
Control | Cyclohexane (3.35) | n-Hexane (3.86) | n-Decane (5.98) | Toluene (2.64) | Styrene (2.86) | Ethylbenzene (3.17) | |
1 h | 0.156 | 0.277 | 0.244 | 0.257 | 0.509 | 0.567 | 0.597 |
24 h | 0.234 | 0.362 | 0.370 | 0.333 | 0.834 | 0.778 | 0.695 |
the absorbance of cell-free supernatant was measured at 260 nm;
logarithm of the partition coefficient of the solvent in octanol-water mixture.