Table 1. Forward mutation frequencies of recessive lethal mutations induced by mitomycin C.
| Batch | Dose (µM) | Number of F1s Tested | Number of Lethal Mutations | Forward Mutation Frequency (%)a |
|---|---|---|---|---|
| 1 | 750 | 437 | 24 | 5.5 |
| 1 | 750 | 550 | 25 | 4.5 |
| 1 | 750 | 436 | 24 | 5.5 |
| 2 | 375 | 145 | 3 | 2.1 |
| 2 | 750 | 580 | 13 | 2.2 |
| 2 | 1400 | 145 | 1 | 0.7 |
Forward mutation frequency was calculated as a percentage of lethal mutations – (isolated lethal mutations/F1s tested) × 100%. Refer to text for details.