Table 1. Monoclonal antibodies to CS/DS proteoglycans used in this study detailing their specificity and references describing their characterization.
Antibody | Isotype | Specificity | Reference |
---|---|---|---|
3-B-3 |
IgM |
native CS/DS sulphation epitopes;
also, C-6-S neoepitope “stubs”after digestion with chondroitinase |
[31,33] |
3-C-5 |
IgG |
native CS/DS sulphation epitopes |
[22,31,35] |
4-C-3 |
IgM |
native CS/DS sulphation epitopes |
[22,31,35] |
6-C-3 |
IgM |
native CS/DS sulphation epitopes |
[22,31,35] |
7-D-4 | IgM | native CS/DS sulphation epitopes | [22,31,35] |