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. 2016 Jan 7;11(1):e0146149. doi: 10.1371/journal.pone.0146149

Table 4. Opinion of general practitioners (n = 1229) and rheumatologists (n = 110) on interventions by general practitioners in patients with inflammatory rheumatic diseases.

General practitioners Rheumatologists p value *
Therapy with glucocorticoids by the GP before referral
    no 98 (8%) 35 (32%)
    sometimes a 583 (49%) 62 (57%)
    yes, always 512 (43%) 12 (11%) <0.001
Therapy with DMARDs by the GP before referral
    no 553 (46%) 52 (47%)
    sometimes a 401 (34%) 41 (37%)
    yes, always 243 (20%) 17 (15%) 0.440
Clinical check-up and laboratory tests during treatment with DMARDs by the GP
    no 4 (0%) 0 (0%)
    in exceptional cases 42 (4%) 6 (5%)
    yes, but specialist check up every 6 mo. 559 (47%) 32 (29%)
    yes, but specialist check-up every 3 mo. 225 (19%) 63 (57%)
    yes, only by the GP 369 (31%) 9 (8%) 0.387
Administration of biologics performed by the GP
    no 222 (22%) 15 (14%)
    yes 790 (78%) 91 (86%) 0.062
Subsequent prescription of biologics by the GP
    no 108 (9%) 28 (26%)
    yes 1040 (91%) 81 (74%) <0.001

a Restricted to special circumstances (e.g. extraordinarily long waiting times for the rheumatology appointment or limited availability of a rheumatologist)

* p value based on χ2 for trend or Fisher's exact test