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. 2016 Jan 7;11(1):e0146529. doi: 10.1371/journal.pone.0146529

Table 1. Summary of optimized parameters and characteristics for positive mode LC—MS/MS detection of Protease inhibitors.

MRM Parameters
Name Q1 Q3 DP (V) EP (V) CE (V) CXP (V) tr (min)
Lopinavir 629.3 183.3 32 6 30 6 6.64
Lopinavir M1 643.3 250.3 32 6 37 6 6.36
Nelfinavir 568.6 330.4 70 7 50 5 5.42
Nelfinavir M8 584.6 330.4 70 7 50 5 4.49
Ritonavir 721.2 312.2 58 7 25 5 6.41
Hydroxy ritonavir 737.2 340.5 58 7 25 5 5.26