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. 2016 Jan 7;11(1):e0146529. doi: 10.1371/journal.pone.0146529

Table 2. The KD and δAmax of all the PIs with and without methamphetamine.

No Methamphetamine 100 μM Methamphetamine
PIs δAmax KD (μM) δAmax KD (μM)
Lopinavir 0.0070 ± 0.0002 2.5 ± 0.1 0.0078 ± 0.0005 4.1 ± 0.8
Type I Atazanavir 0.0045 ± 0.0002 3.2 ± 0.8 0.0046 ± 0.0002 4.7 ± 0.7
Tipranavir 0.0050 ± 0.0005 3.1 ± 0.1 0.0061 ± 0.0002 4.7 ± 0.4
Nelfinavir 0.0068 ± 0.0001 2.9 ± 0.1 0.0040 ± 0.0003* 1.4 ± 0.3#
Type II Ritonavir 0.0055 ± 0.0003 0.065 ± 0.001 0.0038 ± 0.0003* 0.043 ± 0.001*
Indinavir 0.0044 ± 0.0002 0.174 ± 0.030 0.0039 ± 0.0002 0.086 ± 0.010*

*-indicates a p-value <0.05;

#-Indicates p-value <0.1