Table 2. Bacterial genera detected a in cecum content of mice administered saline (control) or Lactobacillus casei 32G once per day by oral gavage sorted based on time.
| Taxon | Percentage (mean ± SE) b c | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.5h | 3.5h | 12h | 24h | |||||||||||||
| Control | Low | Medium | High | Control | Low | Medium | High | Control | Low | Medium | High | Control | Low | Medium | High | |
| S24-7 IS | 66.2±15.2 | 61.4±27.7 | 70.4±13.0 | 64.3±25.3 | 75.0±15.8 | 81.3±17.5 | 65.9±5.9 | 69.7±15.6 | 84.6±10.3 | 86.2±5.9 | 78.8±20.3 | 74.1±14.0 | 53.6±22.0 | 70.8±20.7 | 52.9±31.2 | 60.9±18.1 |
| Lachnospiraceae IS | 15.9±9.9 | 26.1±25.0 | 13.8±9.6 | 13.2±8.5 | 8.9±7.2 | 8.0±10.2 | 13.9±8.3 | 2.7±1.6 | 7.1±6.0 | 3.3±2.5 | 12.2±14.6 | 8.8±8.4 | 28.8±19.7 | 12.3±11.3 | 10.7±12.2 | 10.2±6.7 |
| Oscillospira | 10.0±4.7 | 3.8±1.6 | 5.9±3.9 | 4.3±4.1 | 3.3±3.0 | 2.7±3.6 | 2.0±1.3 | 0.8±0.6 | 2.4±2.8 | 1.0±0.6 | 2.1±2.7 | 1.9±1.6 | 7.2±3.3 | 7.1±6.2 | 4.9±4.9 | 4.2±3.1 |
| Ruminococcaceae Other | 2.1±1.2 | 3.2±2.3 | 1.2±0.8 | 2.4±1.9 | 0.6±0.3 | 1.4±0.6 | 0.5±0.2 | 1.5±1.0 | 2.0±1.4 | 3.3±1.9 | 2.0±2.1 | 8.3±4.1 | 2.3±1.4 | 3.2±1.9 | 2.6±2.5 | 2.2±0.9 |
| Ruminococcus | 1.3±0.6 | 1.1±0.7 | 0.4±0.2 | 1.2±1.4 | 0.7±0.4 | 0.5±0.4 | 0.2±0.1 | 0.7±0.8 | 1.0±0.5 | 1.9±1.4 | 0.7±0.8 | 1.2±0.7 | 0.8±0.3 | 1.0±0.3 | 0.6±0.5 | 1.4±1.2 |
| Clostridia Other | 1.2±0.8 | 1.0±0.6 | 0.4±0.4 | 0.7±0.7 | 0.3±0.1 | 0.6±0.6 | 0.2±0.1 | 0.2±0.1 | 0.5±0.5 | 0.6±0.3 | 0.3±0.2 | 0.6±0.5 | 0.9±0.3 | 0.8±1.2 | 0.7±0.7 | 0.8±0.6 |
| Lactobacillus | 0.9±1.6 | 0.5±0.9 | 5.0±4.6 | 11.0±16.4 | 6.8±7.7 | 3.6±6.9 | 15.0±9.6 | 22.2±14.6 | 0.4±0.5 | 0.6±0.9 | 0.6±0.4 | 1.9±2.7 | 3.7±4.3 | 1.1±1.0 | 24.8±17.3 | 16.9±19.5 |
| Lachnospiraceae Other | 0.9±0.4 | 0.9±0.5 | 0.4±0.2 | 0.7±0.6 | 0.3±0.2 | 0.3±0.4 | 0.2±0.1 | 0.2±0.1 | 0.4±0.5 | 0.7±0.8 | 0.3±0.2 | 0.6±0.5 | 0.8±0.4 | 1.1±1.5 | 0.5±0.5 | 0.8±0.4 |
| Clostridiales Other | 0.6±0.3 | 0.6±0.4 | 0.5±0.4 | 0.4±0.4 | 0.1±0.1 | 0.3±0.3 | 0.2±0.1 | 0.1±0.1 | 0.3±0.3 | 0.2±0.1 | 0.3±0.2 | 0.6±0.5 | 0.6±0.3 | 0.5±0.3 | 0.6±0.8 | 0.4±0.2 |
| Ruminococcaceae IS | 0.2±0.1 | 0.3±0.4 | 0.9±0.6 | 0.7±0.9 | 0.3±0.2 | 0.2±0.3 | 0.6±0.3 | 0.8±0.4 | 0.2±0.1 | 0.6±0.7 | 1.0±0.6 | 0.8±0.5 | 0.2±0.1 | 0.4±0.2 | 0.4±0.3 | 0.5±0.2 |
| Firmicutes Other | 0.2±0.1 | 0.1±0.2 | 0.2±0.1 | 0.2±0.2 | 0.2±0.1 | 0.2±0.2 | 0.2±0.1 | 0.2±0.1 | 0.2±0.2 | 0.2±0.1 | 0.2±0.1 | 0.1±0.1 | 0.2±0.1 | 0.4±0.3 | 0.4±0.2 | 0.4±0.2 |
| Bacteria Other | 0.2±0.0 | 0.1±0.1 | 0.3±0.1 | 0.2±0.1 | 0.2±0.1 | 0.2±0.1 | 0.4±0.2 | 0.3±0.1 | 0.2±0.1 | 0.1±0.0 | 0.2±0.1 | 0.4±0.2 | 0.2±0.1 | 0.2±0.1 | 0.3±0.1 | 0.5±0.1 |
| Erysipelotrichaceae IS | 0.1±0.1 | 0.2±0.2 | 0.1±0.1 | 0.0±0.0 | 0.0±0.0 | 0.1±0.0 | 0.1±0.1 | 0.0±0.0 | 0.1±0.1 | 0.1±0.1 | 0.2±0.2 | 0.0±0.0 | 0.0±0.0 | 0.1±0.1 | 0.1±0.0 | 0.1±0.0 |
| Turicibacter | 0.0±0.1 | 0.1±0.2 | 0.0±0.0 | 0.3±0.4 | 2.7±2.6 | 0.2±0.2 | 0.1±0.2 | 0.4±0.7 | 0.4±0.5 | 0.8±0.9 | 0.8±1.1 | 0.4±0.5 | 0.1±0.1 | 0.3±0.3 | 0.0±0.0 | 0.0±0.1 |
| Coprobacillaceae IS | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.1±0.1 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.0±0.0 | 0.2±0.2 | 0.0±0.0 | 0.0±0.0 |
| Adlercreutzia | BQL | 0.1±0.1 | 0.2±0.1 | 0.0±0.0 | 0.2±0.5 | 0.1±0.2 | 0.3±0.2 | 0.1±0.0 | 0.1±0.2 | 0.1±0.2 | 0.2±0.1 | 0.0±0.0 | 0.1±0.0 | 0.2±0.3 | 0.2±0.2 | 0.1±0.1 |
| Coriobacteriales IS | BQL | BQL | BQL | BQL | 0.0±0.0 | BQL | BQL | BQL | BQL | BQL | BQL | BQL | 0.0±0.0 | 0.0±0.0 | BQL | 0.2±0.2 |
| Number of alterations d | - | 2 | 8 | 4 | - | 3 | 6 | 6 | - | 2 | 2 | 6 | - | 5 | 7 | 9 |
aOnly genera that were present at ≥1% in a sample are included in this table.
bThe detection limit was 0.00003 and this value was used to calculate the p-value.
cGenera that differ from control within each group are shown in bold (p≤0.05).
dThe number of genera that differed from the control for that treatment.
IS: Incertae Sedis.
BQL: Below quantifiable limit.