Table 5.
Overview of the ORN events (crude rates) in the cohort at risk, related to surgery and IMRT sequence
| Patients with mandible exposed to > 60 Gy (N = 531) | ||||||||
|---|---|---|---|---|---|---|---|---|
| IMRT sequence | Definitive IMRT (n = 282) | Postoperative IMRT (n = 249)) | ||||||
| Site | SG | OCC | MC | MC | SG | OCC | ||
| No mandibular surgery (n) | 3/3 | 52/52 | 227/227 | 72/74 | 66/69 | 46/106 | ||
| With mandibular surgery (n) | 0 | 0 | 0 | 2/74 | 3/69 | 60/106 | ||
| ORN | 0 % (0/3) | 2 % (1/52) | 7 % (16/227) | 0 % (0/74) | 33 % (1/3) | 0 % (0/66) | 25 % (15/60) | 7 % (3/46) |
MC mesopharyngeal carcinoma, OCC oral cavity cancer, SG salivary gland tumor.