Phylogenetic analysis of AcCATPO and other plant catalases. Sequences were retrieved from a basic local alignment search (BLAST) (National Center for Biotechnology Information, NCBI). The AcCATPO (marked by triangle) sequence obtained was used as a query selecting results with total score >800 (E = 0, except sectorial sequences). Accession codes (GenBank) for catalase sequences from betalain-producing plants (marked by ellipses, Clades 1 and 2) are: Beta vulgaris subsp. vulgaris 1,2 (gi:731361773, 731361778), Beta vulgaris subsp. Maritime (gi:564116010), Mesembryanthemum crystallinum root, leaf (gi:3202034, 3202032), Rheum australe (gi:197312885), Hylocereus undatus (gi:571032250), Bassia scoparia (gi:686477557), and Suaeda salsa (gi:20138726). Amaranthus cruentus K: AA of mira_lrc70 CDS from the Amaranthus cruentus cv. Kerala transcriptome (Hatlestad et al., 2012). Accession codes for the non-betalain-producing plants: Prunus mume 1,2 (gi:645265094, 645265092), Gardenia jasminoides (gi:721750661), Nicotiana tabacum 1,2 (gi:429535123, 2459684), Prunus persica (gi:32526568), Nicotiana benthamiana (gi:219560127), Vitis vinifera 1,2,3,4 (gi:526117723, 359476986, 819330654, 731427403), Nicotiana sylvestris (gi:698496386), Prunus avium (gi:121078773), Nicotiana tomentosiformis (gi:697176653), Solanum tuberosum (gi:565347640), Eucalyptus grandis 1,2 (gi:702368481, 702368496), Solanum lycopersicum (gi:854282574), Tarenaya hassleriana 1,2,3 (gi:729311669, 729453171, 729330417), Musa acuminata subsp. malaccensis (gi:695050168), Theobroma cacao 1,2 (gi:590701975, 590595360), Sesamum indicum 1,2,3 (gi:749385032, 747055694, 747055696), Brassica juncea 1,2,3,4 (gi:4336754, 4336756, 4336758, 4336752), Camelina sativa 1,2,3 (gi:727512115, 727548051, 727523245), Ipomoea batatas 1,2 (gi:282935438, 115703), Raphanus sativus 1,2 (gi:8050693, 7302765), Ziziphus jujuba (gi:357966938), Brassica rapa (gi:685256782), Jatropha curcas 1,2 (gi:802555337, 806776603), Nicotiana glutinosa (gi:2253291), Arabis alpina (gi:674237382), Arabidopsis thaliana 1,2,3,4 (gi:15236264, 1246399, 15451166, 444340), Brassica oleracea (gi:259122789), Brassica napus (gi:169244543), Solanum melongena (gi:562787), Genlisea aurea (gi:527202914), Gossypium arboretum 1,2 (gi:728845709, 728833533), Gossypium hirsutum (gi:211906480), Eriobotrya japonica (gi:442736195), Gossypium raimondii (gi:823132870), Hevea brasiliensis (gi:315937176), Elaeis guineensis (gi:743775712), and Citrus sinensis (gi:568839653).