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Diagram of VirA and VirG. VirA and VirG are arranged in functional domains. Key amino acids are indicated. H474 is the site of autophosphorylation in the VirA kinase domain. D52 is the aspartate in the VirG receiver domain that accepts the phosphate from VirA. D766N in the VirA receiver domain is analogous to VirG’s D52. RA denotes the receiver domain of VirA and DNAB represents the DNA-binding domain of VirG.
