Table 5.

Association of 12Glu9 polymorphism of ADRA2B gene in relation to different diseases and population of ethnicity.

S. No	Disease	Population	p Value	Association	References
1	Type 2 diabetes mellitus + Hypertension	Malaysian	p = 0.51	No	Vasudevan et al. (2008)
2	Acute coronary events	Finland/Sweden	p = 0.03	Yes	Heinonen et al., 1999, Heinonen et al., 2002
3	Acute coronary events	Finland	p = 0.02	Yes	Snapir et al., 2001, Snapir et al., 2003
4	T2DM + Neuropathy	Greece	p = 0.0008	Yes	Papanas et al. (2007)
5	Insulin Secretion + T2DM	Finland	p = 0.04	Yes	Siitonen et al. (2004)
6	T2DM	Greece	p = 0.40	No	Papazoglou et al. (2006)
7	Sudden cardiac death (SCD)	Finland	p < 0.05	Yes	Laukkanen et al. (2009)
8	Spontaneous recurrent abortions	Greece	p = 0.78	No	Galazios et al. (2011)
9	Migraine	Chinese	p = 0.35	No	Ni et al. (2010)
10	Glucose 6 phosphate dehydrogenase	Saudi	p = 0.68	No	Alharbi et al. (2013)
11	Suicide	Japanese	p = 0.04	Yes	Fukutake et al. (2008)
12	Artery compliance	Chinese	p = 0.73	No	Zhang et al. (2005)
13	Cardiac conduction	Russian	p < 0.05	Yes	Chernova et al. (2013)
14	Hypertension	Scandinavian	p = 0.04	Yes	Von Wowern et al.(2004)
15	Myocardial ischemia + T2DM	Chinese	p < 0.05	Yes	Chen et al. (2010)
16	Obesity	Greece	p > 0.05	No	Sykiotis et al. (2003)
17	Myocardial infarction + SCD	Finland	p = 0.01	Yes	Snapir et al., 2001, Snapir et al., 2003
18	Gestational diabetes mellitus	Saudi	p = 0.0002	Yes	Present study