Table 6.
Genotype distribution of 12Glu9 polymorphism of ADRA2B gene in controls vs different forms of diabetes in relation to ethnicity.
| Genotype/allele | Saudi (n = 500) |
Greece (n = 190) |
Malaysian (n = 210) |
||||
|---|---|---|---|---|---|---|---|
| GDM N (%) | Non-GDM N (%) | Diabetic Neuropathy N (%) | Non-Diabetic Neuropathy N (%) | Controls N (%) | Hypertension N (%) | T2DM N (%) | |
| II | 152 (76) | 265 (88.4) | 72 (55.4) | 46 (76.70) | 6 (8.57) | 7 (10.77) | 18 (24) |
| ID | 35 (17.5) | 28 (9.3) | 46 (35.4) | 14 (23.3) | 34 (48.57) | 28 (43.08) | 35 (46.67) |
| DD | 13 (6.5) | 7 (2.3) | 12 (9.2) | 0 (0) | 30 (42.86) | 30 (46.15) | 22 (29.33) |
| ID + DD | 48 (24) | 35 (11.6) | 60 (44.6) | 14 (23.3) | 64 (91.43) | 58 (89.23) | 57 (76) |
| I | 339 (84.8) | 558 (93) | 190 (73.07) | 106 (88.3) | 46 (32.86) | 42 (32.31) | 71 (47.33) |
| DD | 61 (15.2) | 42 (7) | 70 (26.93) | 14 (11.7) | 94 (67.14) | 88 (67.69) | 79 (52.67) |
| OR | 2.3 (1.5,3.6) | 2.789 (1.4–5.1) | 0.545 (0.3–0.8) | ||||
| p-Value | p = 0.0002 | p = 0.0008 | p = 0.012 | ||||