FIGURE 1.

Trimethyltin (TMT) increases both heme oxygenase-1 (HO-1) and biliverdin reductase (BVR) expression in SH-SY5Y cells. SH-SY5Y cells were treated with TMT (1–10 μM) for 24 h and Western Blot was performed as described in the section “Materials and Methods.” (A) shows representative gels regarding HO-1 and BVR protein expression. Bar graphs represent the quantification of HO-1 (B) and BVR (C) protein levels normalized for β-actin expression. Data are expressed as a mean ± SEM of 4–7 replicates per group. ^∗∗P < 0.01 vs. controls. C, controls.