Table 1. Diagnosis of postinfectious bronchiolitis obliterans.

History of lower respiratory infection, particularly adenovirus, mycoplasma, or measles.

Persistent airway obstruction symptoms and signs, or recurrent airway obstruction symptoms and signs in a mild form.

Sign of obstruction: FEV1/FVC <0.8 or FEV1 percent predicted <80%.

Irreversible airway obstruction demonstrated by lung function test: absent BDR, but positive BDR in some patients.

CT (inspiration and expiration): mosaic perfusion, air trapping, and/or bronchiectasis.

Exclusion of other chronic lung disease (asthma, BPD, chronic aspiration, PCD, cystic fibrosis, and immunodeficiency).

Postinfectious bronchiolitis obliterans is clinically diagnosed when all of the above criteria are met.

FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; BDR, bronchodilator response; BPD, bronchopulmonary dysplasia; CT, computed tomography; PCD, primary ciliary dyskinesia.