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N-terminal truncation activates the LHR. COS-7 cells were transfected with the indicated LHR constructs, and cAMP levels were determined with p10 (2 mm) and without. Empty pcDps vector (mock) served as negative control (pcDps; cAMP level was 1.2 ± 0.2). Data are means ± S.E. of three independent experiments performed in triplicate.
