TABLE 2.
Complexes with low levels of Ctt1-GFP under basal and H2O2-treated conditions
| Name of the complex or pathway | Deletion mutants revealed in the screen | Levels of Ctt1-GFP (unt./H2O2)a |
|---|---|---|
| Oxidative stress pathways | Δsty1 | 0.44/0.19 |
| Δpap1 | 0.75/0.48 | |
| Δcsx1 | 0.41/0.45 | |
| Δatf1 | 0.53/0.37 | |
| Δwin1 | 0.60/0.45 | |
| Δwis4 | 0.54/0.33 | |
| Δpcr1 | 0.51/0.41 | |
| Δmcs4 | 0.56/0.38 | |
| SAGA complex | Δgcn5 | 0.41/0.51 |
| Δada2 | 0.60/0.47 | |
| Δngg1 | 0.36/0.19 | |
| Elongator complex | Δelp3 | 0.85/0.75 |
| Δelp6 | 0.87/0.40 | |
| Δelp4 | 1.02/0.73 | |
| Δiki3 | 0.93/0.69 | |
| Mediator complex | Δsep11/pmc6 | 0.54/0.63 |
| Paf1 complex | Δpaf1 | 1.07/0.74 |
| Δrtf1/prf1 | 0.64/0.59 | |
| Δleo1 | 0.94/1.09 | |
| COMPASS/Set1 complex | Δset1 | 0.47/0.28 |
| Δspf1 | 0.56/0.40 | |
| Δswd1 | 0.64/0.44 | |
| Δswd3 | 0.64/0.40 | |
| Δshg1 | 0.73/0.74 | |
| Δash2 | 0.75/0.88 | |
| Trm112-containing dimers | Δtrm112 | 0.60/0.59 |
| Δmtq2 | 0.58/0.50 | |
| Δtrm9 | 0.87/0.64 |
a Levels of Ctt1-GFP fluorescence in Δgene cells under untreated/H2O2-treated conditions normalized to wild-type cells, with an assigned value at both untreated and treated conditions of 1.