Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 12;291(2):904–912. doi: 10.1074/jbc.M115.674663

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 10. — Schema of FGF-10-induced ERK1/2 phosphorylation regulated by Cx43. PDGF-A and PDGF-B induce the expression of FGF7 and FGF10 in SMG mesenchymal cells. Cx43 does not affect the expression of FGF10 induced by PDGFs, because of the present findings of no expression in SMG mesenchyme. Gap junctional communication or the Cx43 hemichannel has an effect on ERK1/2 phosphorylation induced by FGF10 in SMG epithelium, indicating that Cx43 is necessary for FGF, but not PDGF-induced branching morphogenesis of SMG tissues.