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. 2016 Jan 8;8(1):1–8. doi: 10.4254/wjh.v8.i1.1

Table 1.

Summary of metabolomic studies of chronic hepatitis B

Ref. Year Species Tissue Platform Up-regulated Down-regulated
Zhou et al[23] 2012 Human Serum LC-MS Cortisol, GCA, GCDCA, LysoPC (15:0), LysoPE (22:6), C16:1-CN Tryptophan, C10-CN, C10:1-CN, C8-CN, C6-CN
CHB 30 N 30
CHB/N
Soga et al[24] 2011 Human Serum CE-TOM γ-Glu-Thr
CHB 7 N53 LC-MS
CHB/N

CHB: Chronic hepatitis B; LC-MS: Liquid chromatography-mass spectrometry; GCA: Glycocholic acid; GCDCA: Glycochenodeoxycholic acid; LysoPC: Lysophosphatidylcholine; LysoPE: Lysophosphatidylethanolamine; CN: C16:1-acylcarnitine.