Table 7.
Summary of the clinical characteristics about PVS |
The true incidence of PVS is not really known, but is thought to be < 3% |
The major complication of PVS is the evolution to PVT if not treated |
The majority of patients with PVS are asymptomatic and the diagnosis of stenosis is an incidental finding detected on routine DUS screening |
Risk factors of PVS are almost exclusively represented by technical errors, particularly if a tapered anastomosis is required in the case of a vessel size mismatch between donor and recipient |
Pre-OLT radiotherapy is another major predisposing factor of PVS |
DUS with the finding of a stenosis ratio > 50% or a portal velocity ratio > 3:1 defines PVS. Contrast-enhanced CT and portography are used to confirm the diagnosis |
If PVS is asymptomatic, no therapeutic intervention with close surveillance is possible, but anticoagulation therapy is recommended |
In patients with clinical manifestations, percutaneous radiological intervention is the method of choice by transhepatic or transjugular access to perform angioplasty with our without stent placement; this prevents recurrence with a high rate of success and low rate of complications |
PVT: Portal vein thombosis; PVS: Portal vein stenosis; DUS: Doppler ultrasound; OLT: Orthotopic liver transplantation; CT: Computed tomography.