Table 1.

Inhibition of cytokine, chemokine and other immune modulators by mycolactone.

Summary of findings of multiple publications that have reported the effect of mycolactone directly on the production of various cytokines, chemokines and other proteins by monocytes (Simmonds et al., 2009), macrophages (Hall et al., 2014), dendritic cells (Coutanceau et al., 2007), primary T‐cells (Phillips et al., 2009, Guenin‐Mace et al. 2011), T‐cell lines (Pahlevan et al., 1999, Boulkroun et al., 2010) and endothelial cells (Ogbechi et al., 2015). Colour coding is as follows: Red, profound inhibition; orange, some inhibition; yellow, little inhibition; green, no inhibition; dark green, increased expression; white, not studied