Skip to main content
. 2016 Jan 8;6:19083. doi: 10.1038/srep19083

Figure 2. Dietary impacts on colonic ACF.

Figure 2

Dietary patterns in phase 1 and phase 2 altered total colonic ACF numbers at the end of the study (60 weeks) (a,b). HF diet and ER diet in phase 1 (before and during colon carcinogenesis initiation) enhanced ACF numbers at the end of the study (a). In phase 2 (progression phase of carcinogenesis), HF diet increased ACF burden at the end of the study, compared to CON and ER diet (b). Pair-wise comparisons among nine combinations of dietary patterns in the lifespan showed similar trends (c), with mice in E-H (ER-HF) group showing the most burden of ACF compared to other groups. Different letters denote significant differences in total number of ACF. p < 0.05; two-way ANOVA and Bonferroni adjustment. Data are means ± SEM.