Skip to main content
. 2016 Jan 8;6:19083. doi: 10.1038/srep19083

Table 1. Relative abundances of phyla and genera changed by diet intervention (%, means ± SEM).

Phase 1 diet (wks 3 to 21) Control (C)
High-fat (H)
Energy restriction (E)
p
Phase 2 diet (wks 22 to 60) C H E C H E C H E
Bacteroidetes 43.7 ± 3.6a 43.4 ± 3.5a 30.9 ± 2.0a 29.4 ± 5.7a 32.7 ± 4.9a 32.3 ± 2.9a 44.4 ± 4.1a 45.9 ± 4.7a 39.0 ± 2.0a 0.0007
 Bacteroidia  
  Prevotella 1.2 ± 1.0a 7 ± 0.9b 0.5 ± 0.6a 0.2 ± 1.6a 0.5 ± 1.3a 0.6 ± 0.8a 0.8 ± 1.1a 3 ± 1.3ab 1.1 ± 0.6a <0.0001
  Unknown genus in Rikenellaceae 14 ± 1.1a 13 ± 1.0a 4.1 ± 0.6b 5.9 ± 1.7bc 12 ± 1.5ac 5 ± 0.9b 10 ± 1.2ac 13 ± 1.4ac 6 ± 0.6b <0.0001
  Unknown genus in S24-7 4.5 ± 0.7ac 1.3 ± 0.7a 2.6 ± 0.4ab 3.9 ± 1.1abd 3.8 ± 0.9bc 2.8 ± 0.5abc 8.1 ± 0.8d 5.5 ± 0.9cd 3.5 ± 0.4bc <0.0001
  Bacteroides 16 ± 2.3ab 16 ± 2.2ab 17 ± 1.3ab 15 ± 3.7ab 12 ± 3.2b 16 ± 1.9ab 18 ± 2.7ab 15 ± 3.1ab 22 ± 1.3a 0.0107
  Parabacteroides 7.2 ± 0.8ab 5.3 ± 0.7b 5.1 ± 0.4ab 3.7 ± 1.2ab 4.2 ± 1.0ab 7.1 ± 0.6a 6.1 ± 0.9ab 6.9 ± 1.0ab 5.9 ± 0.4ab 0.0021
Deferribacteres 4.5 ± 2.2ab 1.7 ± 2.1b 8.8 ± 1.2a 6.2 ± 3.5ab 3.7 ± 3.0ab 8.3 ± 1.8a 2.8 ± 2.5b 4.4 ± 2.9ab 3.8 ± 1.3ab 0.0031
 Deferribacteres
  Mucispirillum 4.5 ± 2.2ab 1.7 ± 2.1b 8.8 ± 1.2a 6.2 ± 3.5ab 3.7 ± 3.0ab 8.3 ± 1.8a 2.8 ± 2.5b 4.4 ± 2.9ab 3.8 ± 1.3ab 0.0031
Firmicutes 47.7 ± 3.6a 46.3 ± 3.5a 58.0 ± 2.0a 61.1 ± 5.8a 62.2 ± 5.0a 56.7 ± 2.9a 46.4 ± 4.2a 46.8 ± 4.8a 55.4 ± 2.1a 0.0034
 Bacilli
  Lactobacillus 0.4 ± 1.6b 0.3 ± 1.5b 7.6 ± 0.9a 2.2 ± 2.5b 2.1 ± 2.2b 8 ± 1.3a 2.1 ± 1.8b 1.7 ± 2.1b 8.7 ± 0.9a <0.0001
 Clostridia
  Unknown genus in Clostridiales 25 ± 2.9abc 23 ± 2.8c 28 ± 1.6abc 41 ± 4.6a 38 ± 4.0ab 25 ± 2.3abc 20 ± 3.3bc 26 ± 3.8abc 25 ± 1.6abc 0.0022
  Unknown genus in Lachnospiraceae 3.4 ± 0.8ab 4.8 ± 0.7ab 3.9 ± 0.4ab 5.3 ± 1.2ab 6.4 ± 1.1a 4.1 ± 0.6ab 1.8 ± 0.9b 4.9 ± 1.0ab 4.1 ± 0.4ab <0.0190
  Unknown genus in Ruminococcaceae 1.8 ± 0.3a 3.0 ± 0.3a 2.3 ± 0.2a 1.2 ± 0.5a 2.8 ± 0.4a 2.3 ± 0.3a 1.5 ± 0.4a 1.7 ± 0.4a 2.1 ± 0.2a <0.0449
  Ruminococcus 2.3 ± 0.4abc 1.2 ± 0.4b 2.8 ± 0.2ac 1.0 ± 0.7bc 0.9 ± 0.6b 3.4 ± 0.3a 4.2 ± 0.5a 0.9 ± 0.5b 1.7 ± 0.2b <0.0001
 Erysipelotrichi
  Allobaculum 2.1 ± 0.8ac 0.6 ± 0.7b 1.4 ± 0.4abc 1.0 ± 1.2abc 0.3 ± 1.1b 0.5 ± 1.0abc 3.8 ± 0.9a 0.5 ± 1.0bc 2.3 ± 0.4abc <0.0001
Verrucomicrobia 2.4 ± 0.5a 2.0 ± 0.5ab 0.6 ± 0.3b 1.9 ± 0.8ab 0.4 ± 0.7b 1.3 ± 0.4ab 3.4 ± 0.6a 1.5 ± 0.6ab 0.9 ± 0.3b <0.0001
 Verrucomicrobiae
  Akkermansia 2.4 ± 0.5a 2.0 ± 0.5ab 0.6 ± 0.3b 1.9 ± 0.8ab 0.4 ± 0.7b 1.3 ± 0.4ab 3.4 ± 0.6a 1.5 ± 0.6ab 0.9 ± 0.3b <0.0001

Different letters denote significant differences in pair-wise comparisons (p < 0.05). p-value in ANOVA for unbalanced sample with Bonferroni adjustment.