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. 2016 Jan 8;6:19073. doi: 10.1038/srep19073

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Copyright © 2016, Macmillan Publishers Limited

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(a,b) The semitendinosus tendon was harvested. (c,d) Drilled tunnels (1.5 mm) were created through the femur (c) and tibia (d) at the insertion of the native ACL. (e) The graft was passed through the bone tunnels to replace the ACL. (f) Using a special needle equipped with fibrin glue, we mixed 0.2 ml of the fibrin glue with 1 × 10⁶ Runx2-ADSCs. (g,h) Injection around the periphery of the bone tunnel of the femur (g) and tibia (h) surrounding the tendon graft. Representative images from 10 replications are shown.