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. 2016 Jan 8;6:19106. doi: 10.1038/srep19106

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Copyright © 2016, Macmillan Publishers Limited

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(A) Representative current-clamp recording of ongoing spiking activity of cultured hippocampal neurons from offspring of saline (top) and poly I:C (bottom) -injected mothers. (B) Cultured hippocampal neurons of offspring from polyI:C-injected mothers display significantly lower frequency of spontaneous spike discharge compared to that of offspring from saline-injected mothers (F = 1.30 ± 0.20, n = 57 from 6 polyI:C-injected mothers versus F = 2.21 ± 0.27, n = 46 from 6 saline-injected mothers; t(101) = −2.77, p < 0.01).