Table 3. RSFC alternations within basal ganglia-thalamocortical networks in stuttering subjects.
| Seed ROI | Target regions | Talairach |
|||||
|---|---|---|---|---|---|---|---|
| BA | x | y | z | z score | Cluster size | ||
| Stutterers > Controls | |||||||
| L putamen | L superior temporal gyrus | 38 | –32 | 24 | –23 | 3.98 | 93 |
| Controls > Stutterers | |||||||
| L putamen | R medial frontal gyrus | 32 | 16 | 12 | 47 | 3.95 | 90 |
| R SMA | 6 | 8 | 8 | 53 | 2.91 | ||
| R superior frontal gyrus | 10 | 42 | 57 | 16 | 3.77 | 167 | |
| R middle frontal gyrus | 10 | 38 | 49 | 10 | 2.89 | ||
| R inferior frontal gyrus | 47 | 50 | 25 | –1 | 3.81 | ||
| R superior temporal gyrus | 22 | 57 | 6 | 2 | 4.19 | 1269 | |
| R transverse temporal gyrus | 42 | 59 | –15 | 12 | 3.90 | ||
| R superior temporal gyrus | 21 | 57 | –23 | 0 | 3.82 | 209 | |
| R postcentral gyrus | 2 | 48 | –29 | 37 | 4.05 | 620 | |
| R inferior parietal lobule | 40 | 51 | –37 | 44 | 3.75 | ||
| R cingulate | 32 | 16 | 17 | 32 | 3.54 | 76 | |
| R anterior cingulate | 24 | 12 | 21 | 25 | 3.20 | ||
| R cerebellum | 42 | –56 | –24 | 3.45 | 65 | ||
| R putamen | R superior temporal gyrus | 22 | 55 | 8 | –2 | 4.03 | 206 |
| R inferior frontal gyrus | 47 | 58 | 21 | –6 | 2.92 | ||
| L fusiform gyrus | 37 | –44 | –40 | –18 | 3.62 | 224 | |
| L inferior parietal lobule | 40 | –48 | –34 | 50 | 3.60 | 125 | |
| L postcentral gyrus | 5 | –44 | –42 | 61 | 2.70 | ||
The location of the maximum pixel values were expressed in the human brain atlas of Talairach. Z-score correspond to the actual maximum pixel value within the brain region from the SPM (Voxelwise p < 0.005, uncorrected, cluster p < 0.03, corrected, k > 64, Monte Carlo simulation). L = left; R = right; BA = Brodmann’s area. SMA = supplemental motor area.