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. 2016 Jan 8;6:18995. doi: 10.1038/srep18995

Figure 5. Downstream target genes of STAT3 related to proliferation, migration and invasion were up-regulated in HG conditions.

Figure 5

Cyclin D1, vimentin and MMP2, the downstream targets of STAT3, were validated in NG vs. HG cells of KKU-213 and KKU-214 using western blotting. Quantification of each protein was performed using β-actin as an internal control. The expression of each protein was compared between NG and HG by giving NG = 1. The data one representation of two independent experiments. NG and HG = cells were continuously cultured in normal and high glucose media.