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. 2015 Sep 3;44(1):e7. doi: 10.1093/nar/gkv866

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Comparison between kinking and elastica model of DNA bending. (A) Cartoon of the DNA pulley comparing the two conformations: elastic bending (solid curve) and kinking (dotted line). The blue and red sets of lines show that the impact of kinking on bead displacements, dr and dw, depends on the direction of the applied force vector, F. (B) Calculation of dr for experimentally feasible range of F. |F| is the magnitude of the force, and is the angle between F and x-axis. The ability to resolve length changes dr depends on the ratio of dr to the amplitude of the thermal fluctuations along , σ_r. Black contours indicate lines of constant dr/σ_r.

Inline graphic — Comparison between kinking and elastica model of DNA bending. (A) Cartoon of the DNA pulley comparing the two conformations: elastic bending (solid curve) and kinking (dotted line). The blue and red sets of lines show that the impact of kinking on bead displacements, dr and dw, depends on the direction of the applied force vector, F. (B) Calculation of dr for experimentally feasible range of F. |F| is the magnitude of the force, and is the angle between F and x-axis. The ability to resolve length changes dr depends on the ratio of dr to the amplitude of the thermal fluctuations along , σ_r. Black contours indicate lines of constant dr/σ_r.