Figure 5.

Negative contributions of Rad51 to end-to-end fusion and subtelomere destabilization. (A) The effects of the Δrad51 mutation on the STE2 copy numbers in 16 independent colonies of the indicated strains were determined by qPCR, as described in Figure 3D. Loss of Rad51 reduced the STE2 copy number significantly (**P < 0.01 by a Welch's two-tailed t-test). (B) The frequencies of LiCl-resistant colonies in the indicated strains. The Δrad51 mutation increased the frequency of resistant colonies significantly (**P < 0.01 by a Welch's two-tailed t-test). Data are represented as the mean ±SEM of n = 5 replicates.