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Function of brain microvascular endothelial cells.
Brain microvascular endothelial cells (BMECs) have many important functions such as BBB formation, mediating transport, brain vascular contraction and diastole, and paracrine function. BBB: Blood-brain barrier; ET-1: endothelin-1; NO: nitric oxide; TXA2: thromboxane A2; PGI2: prostaglandin I2; BDNF: brain-derived neurotrophic factor; IGF-1: insulin-like growth factor-1; VEGF: vascular endothelial growth factor.
