Table 3. Unadjusted Scores at Baseline and Change from Baseline by Outcome Measure for Participants With (PG) and Without (CG) Prescriptions for Stimulant Medications.
Baseline | Change from Baselineb | |||||
---|---|---|---|---|---|---|
| ||||||
Measure | Comparison Group (CG) Mean (SD), n | Prescription Group (PG) Mean (SD), n | Between- group comparison (p-valuea) | Comparison Group (CG) Mean (SD), n | Prescription Group (PG) Mean (SD), n | Between- group comparison (p-valuea) |
Wechsler IQ Scores | ||||||
Verbal Scale (VIQ) | 85.7 (15.6), 158 | 83.3 (15.7), 54 | 0.33 | -0.2 (9.4), 158 | 2.5 (11.0), 54 | 0.10 |
Performance Scale (PIQ) | 88.9 (17.2), 158 | 88.1 (14.5), 54 | 0.77 | -0.9 (9.8), 158 | 2.8 (10.8), 54 | 0.03 |
CPRS-48 Scale Scores | ||||||
Anxiety | 48.7 (8.1), 145 | 50.9 (12.2), 49 | 0.25 | 0.2 (8.7), 145 | -2.0 (15.0), 49 | 0.29 |
Conduct Problem | 49.1 (12.0), 145 | 56.4 (17.2), 49 | 0.003 | -1.2 (11.4), 145 | -2.5 (15.8), 49 | 0.58 |
Hyperactivity Index | 50.4 (13.4), 145 | 61.4 (16.8), 49 | <0.001 | -0.9 (12.4), 145 | 1.4 (17.9), 49 | 0.36 |
Impulsive-Hyperactive | 50.0 (12.0), 145 | 60.7 (14.3), 49 | <0.001 | -1.4 (11.7), 145 | -1.6 (16.3), 49 | 0.94 |
Learning Problem | 52.8 (15.4), 145 | 63.0 (16.9), 49 | <0.001 | 0.2 (13.5), 145 | 4.7 (19.8), 49 | 0.12 |
Psychosomatic | 54.3 (14.6), 145 | 54.7 (15.8), 49 | 0.88 | 0.3 (14.8), 145 | 0.4 (18.8), 49 | 0.97 |
QOL Domain Scores | ||||||
General Health Perception | 84.8 (16.0), 378 | 79.4 (17.4), 131 | 0.002 | 1.4 (19.0), 378 | -0.8 (22.0), 131 | 0.31 |
Health Care Utilization | 95.4 (6.9), 380 | 95.0 (6.2), 131 | 0.56 | 0.4 (8.3), 380 | 0.4 (8.0), 131 | 0.91 |
Social/School Functioning | 90.2 (11.5), 377 | 90.3 (12.1), 130 | 0.97 | -0.4 (12.9), 377 | 0.2 (11.3), 130 | 0.59 |
Behavior Problems Index | 82.9 (13.6), 357 | 69.1 (21.6), 124 | <0.001 | 0.6 (12.5), 357 | 0.3 (17.8), 124 | 0.88 |
Estimated using unadjusted generalized estimating equation models.
Mean changes from baseline in Wechsler IQ scores, CPRS-48 scale scores, and QOL domain scores were not significantly different from zero in either the Prescription or Comparison groups, using one-sample t-tests.