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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Pediatr Infect Dis J. 2016 Jan;35(1):71–77. doi: 10.1097/INF.0000000000000926

Table 3.

Regression analyses of length-for-age z-scores (LAZ) at birth and their evolution over time by exposure to antiretroviral drugs (ARV).

Univariable linear regression of LAZ at birth N=531
Multivariable linear regression of LAZ at birth* N=319
Difference in LAZ (95%CI**) P-value Difference in LAZ (95%CI**) P-value
ARVs in the first trimester −0.56 (−0.25 to 0.06) 0.11 −0.05 (−0.41 to 0.30) 0.76
No ARVs during pregnancy −0.21 (−0.50 to 0.08) 0.15 0.26 (−0.23 to 0.75) 0.30
ARVs in the second or third trimester 0 (reference) - 0 (reference) -
Univariable mixed-effects regression of LAZ over time (N=577)
Multivariable mixed-effects regression of LAZ over time (N=356)
Difference in LAZ (95%CI**) P-value Difference in LAZ (95%CI**) P-value
ARVs in the first trimester −0.27 (−0.52 to −0.01) 0.04 −0.35 (−0.63 to −0.08) 0.01
No ARVs during pregnancy −0.23 (−0.45 to −0.001) 0.05 0.12 (−0.25 to 0.49) 0.53
ARVs in the second or third trimester 0 (reference) - 0 (reference) -
**

CI, confidence interval; ARV, antiretroviral therapy; LAZ, length-for-age z-score

*

Adjusted for mother's age (younger than 25 years or older), CD4 cell count (square root transformed), viral load (undetectable or detectable), year of birth, and family income.N=356 children