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. 2015 Dec 10;74(2):ftv117. doi: 10.1093/femspd/ftv117

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© FEMS 2015.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Angiogenin can influence mammalian cell growth and survival. Angiogenin (ANG) acts as a stress/damage sensor that can influence cell growth (as demonstrated with certain cancers) or cell survival (as demonstrated with neurons). Angiogenin is upregulated in various cancers and downregulated in the neurodegenerative diseases shown (ALS, amyotrophic lateral sclerosis; PD, Parkinson's disease). The illustration only reflects two of the major processes influenced by angiogenin in this emerging field, not all of its known effects.