Table 2. Literature review age-related studies of synovial sarcoma patients with localised disease at diagnosis.

Study	Nr of patients	Age groups	Stage	Outcome	P-value
Present study	461	<18 years	Localised disease	5-year OS 89%	<0.001*
				10-year OS 77%
		18–34 years		5-year OS 73%
				10-year OS 64%
		35–64 years		5-year OS 55%
				10-year OS 48%
		⩾65 years		5-year OS 43%
				10-year OS 28%
Palmerini et al (2009)	250	<18 years	Localised disease	5-year OS 89%	0.09*
		18–65 years		5-year OS 71%
		>65 years		5-year OS 73%
Ferrari et al (2004)	215	>16 years	Localised disease, with macroscopic resection	5-year OS 78.5%	Not reported
		17–30 years		5-year OS 72.4%
		>30 years		5-year OS 66.0%
Guadagnolo et al (2007)	150	>20 years	Localised disease	10-year OS 69%	0.04*
		>20 years		10-year OS 54%
Ferrari et al (2014)	138	<10 years	Localised disease	3-year OS 100%	0.7827
		10–21 years		3-year OS 96%
Trassard et al (2001)	128	>33 years	Localised disease	5-year DSS 66.9%	0.294
		>33 years		5-year DSS 58.7%
Al-Hussaini et al (2011)	102	>30 years	Localised disease	5-year EFS 70.9%	0.47
		>30 years		5-year EFS 68.6%
Brennan et al (2010)	77	>11 years	Localised disease	5-year OS 81%	0.60
		12–20 years		5-year OS 80%
Tarkan et al (2014)	69	<40 years	Stage I–III	5-year OS 63%	0.808
		>40 years		5-year OS 65%
Yaser et al (2014)	51	<20 years	Localised disease	5-year OS 100%	0.042*
		⩾20 years		5-year OS 55.2%

Abbreviations: DSS=disease-specific survival; EFS=event-free survival; OS=overall survival; RR=relative survival.

*P-value based on the multivariable analysis. The significant P-values are highlighted in bold.