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. 2015 Oct 15;290(50):29964–29973. doi: 10.1074/jbc.M115.674010

FIGURE 3.

FIGURE 3.

B7-H6 expression in tumor cells correlates to their susceptibility to NK killing. A and B, HEK293 cells were transduced with lentivirus delivering scramble shRNA (shScr) or shRNA targeting B7-H6 (shB7-H6-1, shB7-H6-2), and B7-H6 expression was then analyzed by real-time PCR (A) and Western blotting (B). C, lysis of HEK293 cells transduced with shScr, shB7-H6-1 or shB7-H6-2 by NK-92 cells was determined in a 4 h cytotoxicity assay. D, lysis of K562, HL60, U937, or HeLa cells transduced with shScr, shB7-H6-1, or shB7-H6-2 by NK-92 cells was determined in a 4 h cytotoxicity assay.