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. 2015 Jul 31;4:445. [Version 1] doi: 10.12688/f1000research.6827.1

Figure 2.

Figure 2.

( A) A decrease in 50% withdrawal threshold was observed in both females and males as the disease progressed. ( B and C) Males demonstrated a significant decrease in limb use and weight-bearing ratio on day 17–23. In contrast, females showed significant decrease limb use only on day 23, and decreased weight-bearing on day 17 and 23. ( D) A significant decrease in relative bone density was observed in the males from day 14. A similar, yet insignificant, tendency was observed in the females. * /** /***=males compared to baseline, #/##=females compared to baseline.