Skip to main content
. 2015 Nov 24;25(2):254–265. doi: 10.1093/hmg/ddv468

Figure 7.

Figure 7.

Aberrant transcriptome profile contributes to defective RBM20 cardiogenesis. (A) and (B) Comparative transcriptome analysis of control (n = 3, biological repetitions with three technical replicates for each biological repetition, at each time point) and RBM20 familial DCM (n = 3, biological repetitions with three technical replicates for each biological repetition, at each time point) hiPSC lines during in vitro cardiogenesis identified the top 50 divergent gene expression profiles that were downregulated (A) or upregulated (B) in the RBM20 DCM group compared with control. (C) and (D) GO enrichment analysis revealed corresponding functions in RBM20 patient 1 (C) and RBM20 patient 2 (D), showing a common function of the pattern specification process in both RBM20 familial DCM patients.