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The performance of combined AFP-L3 and GP73 assays for diagnosing AFP-negative HCC
| Detection model | Sensitivity (%) | Specificity (%) | Accuracy (%) |
|---|---|---|---|
| AFP-L3 (+) and GP73 (+) | 40.0 (20/50) | 100 (80/80) | 76.9 (100/130) |
| AFP-L3 (+) and GP73 (−) | 10.0 (5/50) | 98.8 (79/80) | 64.6 (84/130) |
| AFP-L3 (−) and GP73 (+) | 20.0 (10/50) | 98.8 (79/80) | 68.5 (89/130) |
| AFP-L3 (−) and GP73 (−) | 6.0 (3/50) | 93.7 (75/80) | 60.0 (78/130) |
Abbreviations: AFP, alpha-fetoprotein; GP73, Golgi protein 73; HCC, hepatocellular carcinoma.
