FIG. 7.

IFN-γ production by HLA-unrestricted CD8⁺-T-cell clones was not inhibited by antibodies to CD1. IFN-γ production by two HLA-unrestricted clones (clone 1, white bars; clone 2, black bars) in responses to autologous C. trachomatis-infected DC, alone or in the presence of antibodies specific for CD1a, CD1b, CD1c, CD1d, or w6/32. IgG1 and IgG2a isotype control antibodies were also included. Minimal IFN-γ was seen in cultures containing T cells and uninfected DC or in C. trachomatis-infected DC and T cells cultured separately. The experiments were carried out three times for each clone tested. CT, C. trachomatis.