Table 1.
Demographic and clinical characteristics for physically active and sedentary HIV + individuals
| HIV + Physically Active (n = 22) | HIV + Sedentary (n = 48) | p-value | |
|---|---|---|---|
| Age, years, mean (SD) | 44.1 (17.2) | 40.5 (15.6) | 0.34 |
| Sex, (%) | 0.18 | ||
| Male | 23 | 42 | |
| Female | 77 | 58 | |
| Race, (%) | 1.00 | ||
| African American | 73 | 75 | |
| White | 27 | 25 | |
| Education, years, mean (SD) | 14.0 (2.7) | 12.6 (2.6) | 0.034 |
| Nadir CD4, cells/μL, mean (SD) | 207 (185) | 275 (202) | 0.23 |
| Current CD4, cells/μL, mean (SD) | 575 (334) | 614 (253) | 0.60 |
| Current plasma log10 HIV VL, copies/mL, mean (SD) | 1.50 (0.52) | 1.59 (0.83) | 0.78 |
| HIV viral load >20 copies/mL, (%) | 24 | 19 | 0.75 |
| Duration of HIV infection, months, mean (SD) | 144.5 (113.3) | 100.5 (71.2) | 0.24 |
| Anti-retroviral Regimen, (%) | 0.92 | ||
| NRTI + NNRTI | 9 (41) | 21 (44) | |
| NRTI + PI | 6 (27) | 14 (29) | |
| NRTI + INST | 4 (18) | 7(15) | |
| Other HAART | 3 (14) | 4 (8) | |
| None | 0 (0) | 2 (4) | |
| Body mass index, kg/m2, mean (SD) | 26.9 (5.9) | 28.5 (7.5) | 0.47 |
| Intracranial volume, cc, mean (SD) | 1,393 (287) | 1,296 (210) | 0.18 |
| Lifetime substance use (%) | |||
| Alcohol | 43 | 42 | 1.00 |
| Opiates | 0 | 2 | 1.00 |
| Crack/cocaine | 14 | 19 | 1.00 |
| Marijuana | 52 | 56 | 1.00 |
| Methamphetamine | 0 | 2 | 1.00 |
| Tobacco | 50 | 54 | 0.80 |
Note. Comparisons used Wilcoxon rank-sum test for continuous variables, and Fisher’s exact test for binary and categorical variables. SD = standard deviation, VL = viral load, NRTI = nucleoside reverse transcriptase inhibitor, NNRTI = non-nucleotide reverse transcriptase inhibitor, PI = protease inhibitor, INSTI = integrase strand transfer inhibitor; HAART = highly active antiretroviral therapy.